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Heidelberg, 20 April 2015 How cells have got molecules surrounded Ground-breaking microscopy techniques have enabled scientists at EMBL Heidelberg to shed new light on how cells perform endocytosis – a function that is key to many cellular processes, such as ingesting nutrients and cell-signalling. The process of endocytosis generates bubble-like membrane vesicles that surround the molecules to be ingested and move them from the cell surface into the cell. In this study, published in Developmental Cell, a cross-disciplinary team from five research groups at EMBL and the European XFEL demonstrates the significance of a particular type of proteins, called clathrin adaptor proteins, to the process.
Heidelberg, 16 March 2015 New technique to chart protein networks in living cells A new approach for studying the behaviour of proteins in living cells has been developed by an interdisciplinary team of biologists and physicists in the Cell Biology and Biophysics Unit, the Ellenberg Laboratory and the Advanced Light Microscopy Facility at EMBL Heidelberg. Described in a new study, published today in Nature Biotechnology, the approach allows scientists for the first time to follow the protein networks that drive a biological process in real time.
Hinxton, 11 March 2015 Ewan Birney and Rolf Apweiler appointed Joint Directors of EMBL-EBI Dr Ewan Birney and Dr Rolf Apweiler have been appointed Joint Directors of the European Molecular Biology Laboratory – European Bioinformatics Institute (EMBL-EBI) as Professor Dame Janet Thornton steps down after 14 years in post. They will assume their new roles with effect from 1 July 2015. Drs Birney and Apweiler have both enjoyed long and distinguished careers at EMBL-EBI, and were appointed Joint Associate Directors in 2012. As Joint Directors, they will share responsibility for all aspects of EMBL-EBI, including services, research, training, industry engagement and European coordination. Dr Birney and Professor Thornton will continue to lead their respective research groups.
Heidelberg, 19 February 2015 Better together A paper published today in the journal PLoS Pathogens by scientists at EMBL Hamburg and collaborators demonstrates the power of bringing together specialists in different areas to tackle complex problems. By joining forces, the multidisciplinary team uncovered a surprise about the bacterium that causes tuberculosis.
Heidelberg, 6 February 2015 The battle for iron The search for therapies against anaemia of chronic disease (ACD) could take on new directions thanks to a study published today in Blood. In it, scientists in the Molecular Medicine Partnership Unit, a joint venture of EMBL and Heidelberg University Clinic, have found a hitherto unknown way through which mice starve pathogens of iron.
Monterotondo, 8 December 2014 Stain every nerve Scientists can now explore nerves in mice in much greater detail than ever before, thanks to an approach developed by scientists at EMBL Monterotondo. The work, published online today in Nature Methods, enables researchers to easily use artificial tags, broadening the range of what they can study and vastly increasing image resolution.
Grenoble, 19 November 2014 In full view Scientists looking to understand – and potentially thwart – the influenza virus now have a much more encompassing view, thanks to the first complete structure of one of the flu virus’ key machines. The structure, obtained by scientists at EMBL Grenoble, allows researchers to finally understand how the machine works as a whole, and could prove instrumental in designing new drugs to treat serious flu infections and combat flu pandemics.
Heidelberg, 3 November 2014 Witamy! EMBL welcomes Poland as prospect member state In a Statement of Intent signed this month, Poland becomes a prospect member state of EMBL, and the new partners agree to explore possibilities for long-term cooperation, with a view to the country becoming a full member state within three years.
Heidelberg, 2 November 2014 Same pieces, different picture Scientists at EMBL Heidelberg have obtained the first structure of the immature form of HIV at a high enough resolution to pinpoint exactly where each building block sits in the virus. The study reveals that the building blocks of the immature form of HIV are arranged in a surprising way.
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