Staff at EMBL
Christoph Philipp Bieniossek
Postdoctoral Fellow (EIPOD)
Berger Group
Schaffitzel Team
EMBL Grenoble, BP 181, 6 rue Jules Horowitz, 38042 Grenoble Cedex 9, France
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Publications
The architecture of human general transcription factor TFIID core complex. Bieniossek, C., Papai, G., Schaffitzel, C., Garzoni, F., Chaillet, M., Scheer, E., Papadopoulos, P., Tora, L., Schultz, P. & Berger, I. Nature. 2013 Jan 31;493(7434):699-702. doi: 10.1038/nature11791. Epub 2013 Jan 6. PubMed
MultiBac: expanding the research toolbox for multiprotein complexes. Bieniossek, C., Imasaki, T., Takagi, Y. & Berger, I. Trends Biochem Sci. 2012 Feb;37(2):49-57. doi: 10.1016/j.tibs.2011.10.005. Epub2011 Dec 7. PubMed
Robots, pipelines, polyproteins: Enabling multiprotein expression in prokaryotic and eukaryotic cells. Vijayachandran, L.S., Viola, C., Garzoni, F., Trowitzsch, S., Bieniossek, C., Chaillet, M., Schaffitzel, C., Busso, D., Romier, C., Poterszman, A., Richmond, T.J. & Berger, I. J Struct Biol. 2011 Mar 17. PubMed
New baculovirus expression tools for recombinant protein complex production. Trowitzsch, S., Bieniossek, C., Nie, Y., Garzoni, F. & Berger, I. J Struct Biol. 2010 Feb 21. PubMed
The crystal structure of apo-FtsH reveals domain movements necessary for substrate unfolding and translocation. Bieniossek, C., Niederhauser, B. & Baumann, U.M. Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21579-84. Epub 2009 Dec 2. PubMed
Getting a grip on complexes. Nie, Y., Viola, C., Bieniossek, C., Trowitzsch, S., Vijay-Achandran, L.S., Chaillet, M., Garzoni, F. & Berger, I. Curr Genomics. 2009 Dec;10(8):558-72. PubMed
ACEMBLing multigene expression constructs by recombineering. Nie, Y., Bieniossek, C., Frey, D., Olieric, N., Schaffitzel, C., Steinmetz, M.O. & Berger, I. Nat Protocols, doi: 10.1038/nprot.2009.104
Automated unrestricted multigene recombineering for multiprotein complex production. Bieniossek, C., Nie, Y., Frey, D., Olieric, N., Schaffitzel, C., Collinson, I., Romier, C., Berger, P., Richmond, T.J., Steinmetz, M.O. & Berger, I. Nat Methods. 2009 Jun;6(6):447-50. Epub 2009 May 3. PubMed
Towards eukaryotic structural complexomics. Bieniossek, C. & Berger, I. J Struct Funct Genomics. 2009 Mar;10(1):37-46. Epub 2008 Nov 14. PubMed
X-ray structures of the three Lactococcus lactis dihydroxyacetone kinase subunits and of a transient intersubunit complex. Zurbriggen, A., Jeckelmann, J.M., Christen, S., Bieniossek, C., Baumann, U. & Erni, B. J Biol Chem. 2008 Dec 19;283(51):35789-96. Epub 2008 Oct 28. PubMed
Crystal structure of the yeast eIF4A-eIF4G complex: an RNA-helicase controlled by protein-protein interactions. Schutz, P., Bumann, M., Oberholzer, A.E., Bieniossek, C., Trachsel, H., Altmann, M. & Baumann, U. Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9564-9. Epub 2008 Jul 7. PubMed
MultiBac: multigene baculovirus-based eukaryotic protein complex production. Bieniossek, C., Richmond, T.J. & Berger, I. Curr Protoc Protein Sci. 2008 Feb;Chapter 5:Unit 5.20. PubMed
Multiprotein expression strategy for structural biology of eukaryotic complexes. Fitzgerald, D.J., Schaffitzel, C., Berger, P., Wellinger, R., Bieniossek, C., Richmond, T.J. & Berger, I. Structure. 2007 Mar;15(3):275-9. PubMed
Nucleic Acid Science - The Excitement of Discovery. Annual Symposium of the Chemical Society Zurich. Berger, I., Schaffitzel, C. & Bieniossek, C. Chimia 2007 61 837-841
Ftsh/HflB. Baumann, U. & Bieniossek, C. Handbook of Metalloproteins, A Messerschmidt & M Cygler (eds), 3rd edition
Regulation of the Dha operon of Lactococcus lactis: a deviation from the rule followed by the Tetr family of transcription regulators. Christen, S., Srinivas, A., Bahler, P., Zeller, A., Pridmore, D., Bieniossek, C., Baumann, U. & Erni, B. J Biol Chem. 2006 Aug 11;281(32):23129-37. Epub 2006 Jun 7. PubMed
The crystal structure of the carboxy-terminal domain of human translation initiation factor eIF5. Bieniossek, C., Schutz, P., Bumann, M., Limacher, A., Uson, I. & Baumann, U. J Mol Biol. 2006 Jul 7;360(2):457-65. Epub 2006 May 24. PubMed
The molecular architecture of the metalloprotease FtsH. Bieniossek, C., Schalch, T., Bumann, M., Meister, M., Meier, R. & Baumann, U. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3066-71. Epub 2006 Feb 16. PubMed
Direct interaction of Ca2+/calmodulin inhibits histone deacetylase 5 repressor core binding to myocyte enhancer factor 2. Berger, I., Bieniossek, C., Schaffitzel, C., Hassler, M., Santelli, E. & Richmond, T.J. J Biol Chem. 2003 May 16;278(20):17625-35. Epub 2003 Mar 6. PubMed