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Staff at EMBL

Simon Trowitzsch

Postdoctoral Fellow
Berger Group

EMBL Grenoble, BP 181, 6 rue Jules Horowitz, 38042 Grenoble Cedex 9, France

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More pieces to the puzzle: recent structural insights into class II transcription initiation. Kandiah, E., Trowitzsch, S., Gupta, K., Haffke, M. & Berger, I. Curr Opin Struct Biol. 2014 Jan 15;24C:91-97. doi: 10.1016/ Europe PMC

Multiprotein complex production in insect cells by using polyproteins. Nie, Y., Bellon-Echeverria, I., Trowitzsch, S., Bieniossek, C. & Berger, I. Methods Mol Biol. 2014;1091:131-41. doi: 10.1007/978-1-62703-691-7_8. Europe PMC

MultiBac complexomics. Trowitzsch, S., Palmberger, D., Fitzgerald, D., Takagi, Y. & Berger, I. Expert Rev Proteomics. 2012 Aug;9(4):363-73. Europe PMC

Light it up: Highly efficient multigene delivery in mammalian cells. Trowitzsch, S., Klumpp, M., Thoma, R., Carralot, J.P. & Berger, I. Bioessays. 2011 Dec;33(12):946-55. doi: 10.1002/bies.201100109. Epub 2011Oct 17. Europe PMC

Robots, pipelines, polyproteins: enabling multiprotein expression in prokaryotic and eukaryotic cells. Vijayachandran, L.S., Viola, C., Garzoni, F., Trowitzsch, S., Bieniossek, C., Chaillet, M., Schaffitzel, C., Busso, D., Romier, C., Poterszman, A., Richmond, T.J. & Berger, I. J Struct Biol. 2011 Aug;175(2):198-208. doi: 10.1016/j.jsb.2011.03.007. Epub 2011Mar 17. Europe PMC

HSPC117 is the essential subunit of a human tRNA splicing ligase complex. Popow, J., Englert, M., Weitzer, S., Schleiffer, A., Mierzwa, B., Mechtler, K., Trowitzsch, S., Will, C.L., Luhrmann, R., Soll, D. & Martinez, J. Science. 2011 Feb 11;331(6018):760-4. Europe PMC

Functional organization of the Sm core in the crystal structure of human U1 snRNP. Weber, G., Trowitzsch, S., Kastner, B., Luhrmann, R. & Wahl, M.C. EMBO J. 2010 Dec 15;29(24):4172-84. Epub 2010 Nov 26. Europe PMC

New baculovirus expression tools for recombinant protein complex production. Trowitzsch, S., Bieniossek, C., Nie, Y., Garzoni, F. & Berger, I. J Struct Biol. 2010 Oct;172(1):45-54. doi: 10.1016/j.jsb.2010.02.010. Epub 2010Feb 21. Europe PMC

Molecular basis of the light-driven switching of the photochromic fluorescent protein Padron. Brakemann, T., Weber, G., Andresen, M., Groenhof, G., Stiel, A.C., Trowitzsch, S., Eggeling, C., Grubmuller, H., Hell, S.W., Wahl, M.C. & Jakobs, S. J Biol Chem. 2010 May 7;285(19):14603-9. doi: 10.1074/jbc.M109.086314. Epub 2010Mar 16. Europe PMC

Coilin-dependent snRNP assembly is essential for zebrafish embryogenesis. Strzelecka, M., Trowitzsch, S., Weber, G., Luhrmann, R., Oates, A.C. & Neugebauer, K.M. Nat Struct Mol Biol. 2010 Apr;17(4):403-9. Epub 2010 Mar 28. Europe PMC

Getting a grip on complexes. Nie, Y., Viola, C., Bieniossek, C., Trowitzsch, S., Vijay-Achandran, L.S., Chaillet, M., Garzoni, F. & Berger, I. Curr Genomics. 2009 Dec;10(8):558-72. Europe PMC

Crystal structure of the Pml1p subunit of the yeast precursor mRNA retention and splicing complex. Trowitzsch, S., Weber, G., Luhrmann, R. & Wahl, M.C. J Mol Biol. 2009 Jan 16;385(2):531-41. Epub 2008 Nov 7. Europe PMC

An unusual RNA recognition motif acts as a scaffold for multiple proteins in the pre-mRNA retention and splicing complex. Trowitzsch, S., Weber, G., Luhrmann, R. & Wahl, M.C. J Biol Chem. 2008 Nov 21;283(47):32317-27. Epub 2008 Sep 22. Europe PMC

Structural basis for reversible photoswitching in Dronpa. Andresen, M., Stiel, A.C., Trowitzsch, S., Weber, G., Eggeling, C., Wahl, M.C., Hell, S.W. & Jakobs, S. Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13005-9. Epub 2007 Jul 23. Europe PMC

1.8 A bright-state structure of the reversibly switchable fluorescent protein Dronpa guides the generation of fast switching variants. Stiel, A.C., Trowitzsch, S., Weber, G., Andresen, M., Eggeling, C., Hell, S.W., Jakobs, S. & Wahl, M.C. Biochem J. 2007 Feb 15;402(1):35-42. Europe PMC

U1 small nuclear ribonucleoprotein immune complexes induce type I interferon in plasmacytoid dendritic cells through TLR7. Savarese, E., Chae, O.W., Trowitzsch, S., Weber, G., Kastner, B., Akira, S., Wagner, H., Schmid, R.M., Bauer, S. & Krug, A. Blood. 2006 Apr 15;107(8):3229-34. Epub 2005 Dec 20. Europe PMC

Structure and mechanism of the reversible photoswitch of a fluorescent protein. Andresen, M., Wahl, M.C., Stiel, A.C., Grater, F., Schafer, L.V., Trowitzsch, S., Weber, G., Eggeling, C., Grubmuller, H., Hell, S.W. & Jakobs, S. Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13070-4. Epub 2005 Aug 31. Europe PMC