Staff at EMBL
Simon Trowitzsch
Postdoctoral Fellow
Berger Group
EMBL Grenoble, BP 181, 6 rue Jules Horowitz, 38042 Grenoble Cedex 9, France
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Publications
MultiBac complexomics. Trowitzsch, S., Palmberger, D., Fitzgerald, D., Takagi, Y. & Berger, I. Expert Rev Proteomics. 2012 Aug;9(4):363-73. PubMed
Light it up: Highly efficient multigene delivery in mammalian cells. Trowitzsch, S., Klumpp, M., Thoma, R., Carralot, J.P. & Berger, I. Bioessays. 2011 Dec;33(12):946-55. doi: 10.1002/bies.201100109. Epub 2011Oct 17. PubMed
Robots, pipelines, polyproteins: Enabling multiprotein expression in prokaryotic and eukaryotic cells. Vijayachandran, L.S., Viola, C., Garzoni, F., Trowitzsch, S., Bieniossek, C., Chaillet, M., Schaffitzel, C., Busso, D., Romier, C., Poterszman, A., Richmond, T.J. & Berger, I. J Struct Biol. 2011 Mar 17. PubMed
HSPC117 is the essential subunit of a human tRNA splicing ligase complex. Popow, J., Englert, M., Weitzer, S., Schleiffer, A., Mierzwa, B., Mechtler, K., Trowitzsch, S., Will, C.L., Luhrmann, R., Soll, D. & Martinez, J. Science. 2011 Feb 11;331(6018):760-4. PubMed
Functional organization of the Sm core in the crystal structure of human U1 snRNP. Weber, G., Trowitzsch, S., Kastner, B., Luhrmann, R. & Wahl, M.C. EMBO J. 2010 Dec 15;29(24):4172-84. Epub 2010 Nov 26. PubMed
Coilin-dependent snRNP assembly is essential for zebrafish embryogenesis. Strzelecka, M., Trowitzsch, S., Weber, G., Luhrmann, R., Oates, A.C. & Neugebauer, K.M. Nat Struct Mol Biol. 2010 Apr;17(4):403-9. Epub 2010 Mar 28. PubMed
Molecular basis of the light-driven switching of the photochromic fluorescent protein Padron. Brakemann, T., Weber, G., Andresen, M., Groenhof, G., Stiel, A.C., Trowitzsch, S., Eggeling, C., Grubmueller, H., Hell, S.W., Wahl, M.C. & Jakobs, S. J Biol Chem. 2010 Mar 16. PubMed
New baculovirus expression tools for recombinant protein complex production. Trowitzsch, S., Bieniossek, C., Nie, Y., Garzoni, F. & Berger, I. J Struct Biol. 2010 Feb 21. PubMed
Getting a grip on complexes. Nie, Y., Viola, C., Bieniossek, C., Trowitzsch, S., Vijay-Achandran, L.S., Chaillet, M., Garzoni, F. & Berger, I. Curr Genomics. 2009 Dec;10(8):558-72. PubMed
Crystal structure of the Pml1p subunit of the yeast precursor mRNA retention and splicing complex. Trowitzsch, S., Weber, G., Luhrmann, R. & Wahl, M.C. J Mol Biol. 2009 Jan 16;385(2):531-41. Epub 2008 Nov 7. PubMed
An unusual RNA recognition motif acts as a scaffold for multiple proteins in the pre-mRNA retention and splicing complex. Trowitzsch, S., Weber, G., Luhrmann, R. & Wahl, M.C. J Biol Chem. 2008 Nov 21;283(47):32317-27. Epub 2008 Sep 22. PubMed
Structural basis for reversible photoswitching in Dronpa. Andresen, M., Stiel, A.C., Trowitzsch, S., Weber, G., Eggeling, C., Wahl, M.C., Hell, S.W. & Jakobs, S. Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13005-9. Epub 2007 Jul 23. PubMed
1.8 A bright-state structure of the reversibly switchable fluorescent protein Dronpa guides the generation of fast switching variants. Stiel, A.C., Trowitzsch, S., Weber, G., Andresen, M., Eggeling, C., Hell, S.W., Jakobs, S. & Wahl, M.C. Biochem J. 2007 Feb 15;402(1):35-42. PubMed
U1 small nuclear ribonucleoprotein immune complexes induce type I interferon in plasmacytoid dendritic cells through TLR7. Savarese, E., Chae, O.W., Trowitzsch, S., Weber, G., Kastner, B., Akira, S., Wagner, H., Schmid, R.M., Bauer, S. & Krug, A. Blood. 2006 Apr 15;107(8):3229-34. Epub 2005 Dec 20. PubMed
Structure and mechanism of the reversible photoswitch of a fluorescent protein. Andresen, M., Wahl, M.C., Stiel, A.C., Grater, F., Schafer, L.V., Trowitzsch, S., Weber, G., Eggeling, C., Grubmuller, H., Hell, S.W. & Jakobs, S. Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13070-4. Epub 2005 Aug 31. PubMed