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Staff at EMBL


Dr. Daniel Panne

Group Leader
Panne Group Joint appointment: Genome Biology Unit

EMBL Grenoble, 71 avenue des Martyrs, CS 90181, 38042 Grenoble Cedex 9, France

E-mail: send a mail


PhD 1999, University of Basel.
Postdoctoral research at Harvard University, Boston.
Group Leader at EMBL Grenoble since 2007.


Total: 15 publication(s)


Panne D. (2013)
Immunology: Cytosolic DNA sensing unraveled
Nat. Chem. Biol. 9(9):533-534. doi:10.1038/nchembio.1318
Europe PMC | doi

Delvecchio M, Gaucher J, Aguilar-Gurrieri C, Ortega E, Panne D. (2013)
Structure of the p300 catalytic core and implications for chromatin targeting and HAT regulation
Nat. Struct. Mol. Biol. 20(9):1040-1046. doi:10.1038/nsmb.2642
Europe PMC | doi

Larabi A, Devos JM, Ng SL, Nanao MH, Round A, Maniatis T, Panne D. (2013)
Crystal structure and mechanism of activation of TANK-binding kinase 1
Cell Rep 3(3):734-746. doi:10.1016/j.celrep.2013.01.034
Europe PMC | doi


Reynoird N, Schwartz BE, Delvecchio M, Sadoul K, Meyers D, Mukherjee C, Caron C, Kimura H, Rousseaux S, Cole PA, Panne D, French CA, Khochbin S. (2010)
Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains
EMBO J. 29(17):2943-2952. doi:10.1038/emboj.2010.176
Europe PMC | doi


Shen A, Higgins DE, Panne D. (2009)
Recognition of AT-rich DNA binding sites by the MogR repressor
Structure 17(5):769-777. doi:10.1016/j.str.2009.02.018
Europe PMC | doi


Panne D. (2008)
The enhanceosome
Curr. Opin. Struct. Biol. 18(2):236-242. doi:10.1016/
Europe PMC | doi


Panne D, McWhirter SM, Maniatis T, Harrison SC. (2007)
Interferon regulatory factor 3 is regulated by a dual phosphorylation-dependent switch
J. Biol. Chem. 282(31):22816-22822. doi:10.1074/jbc.m703019200
Europe PMC | doi

Panne D, Maniatis T, Harrison SC. (2007)
An atomic model of the interferon-beta enhanceosome
Cell 129(6):1111-1123. doi:10.1016/j.cell.2007.05.019
Europe PMC | doi


Panne D, Maniatis T, Harrison SC. (2004)
Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-beta enhancer
EMBO J. 23(22):4384-4393. doi:10.1038/sj.emboj.7600453
Europe PMC | doi


Panne D, Müller SA, Wirtz S, Engel A, Bickle TA. (2001)
The McrBC restriction endonuclease assembles into a ring structure in the presence of G nucleotides
EMBO J. 20(12):3210-3217. doi:10.1093/emboj/20.12.3210
Europe PMC | doi


Stewart FJ, Panne D, Bickle TA, Raleigh EA. (2000)
Methyl-specific DNA binding by McrBC, a modification-dependent restriction enzyme
J. Mol. Biol. 298(4):611-622. doi:10.1006/jmbi.2000.3697
Europe PMC | doi

Evans TC Jr, Martin D, Kolly R, Panne D, Sun L, Ghosh I, Chen L, Benner J, Liu XQ, Xu MQ. (2000)
Protein trans-splicing and cyclization by a naturally split intein from the dnaE gene of Synechocystis species PCC6803
J. Biol. Chem. 275(13):9091-9094. doi:10.1074/jbc.275.13.9091
Europe PMC | doi


Panne D, Raleigh EA, Bickle TA. (1999)
The McrBC endonuclease translocates DNA in a reaction dependent on GTP hydrolysis
J. Mol. Biol. 290(1):49-60. doi:10.1006/jmbi.1999.2894
Europe PMC | doi


Panne D, Raleigh EA, Bickle TA. (1998)
McrBs, a modulator peptide for McrBC activity
EMBO J. 17(18):5477-5483. doi:10.1093/emboj/17.18.5477
Europe PMC | doi

Southworth MW, Adam E, Panne D, Byer R, Kautz R, Perler FB. (1998)
Control of protein splicing by intein fragment reassembly
EMBO J. 17(4):918-926. doi:10.1093/emboj/17.4.918
Europe PMC | doi