PublicationsPillai Group
Crystal structure of the primary piRNA biogenesis factor Zucchini reveals similarity to the bacterial PLD endonuclease Nuc.
Voigt, F., Reuter, M., Kasaruho, A., Schulz, E.C., Pillai, R.S. & Barabas, O.
RNA. 2012 Dec;18(12):2128-34. doi: 10.1261/rna.034967.112. Epub 2012 Oct 19. PubMed
The multiple Tudor domain-containing protein TDRD1 is a molecular scaffold for mouse Piwi proteins and piRNA biogenesis factors.
Mathioudakis, N., Palencia, A., Kadlec, J., Round, A., Tripsianes, K., Sattler, M., Pillai, R.S. & Cusack, S.
RNA. 2012 Nov;18(11):2056-72. doi: 10.1261/rna.034181.112. Epub 2012 Sep 20. PubMed
A Role for Fkbp6 and the Chaperone Machinery in piRNA Amplification and Transposon Silencing.
Xiol, J., Cora, E., Koglgruber, R., Chuma, S., Subramanian, S., Hosokawa, M., Reuter, M., Yang, Z., Berninger, P., Palencia, A., Benes, V., Penninger, J., Sachidanandam, R. & Pillai, R.S.
Mol Cell. 2012 Sep 28;47(6):970-9. doi: 10.1016/j.molcel.2012.07.019. Epub 2012Aug 16. PubMed
Molecular biology. Outsourcing genome protection.
Xiol, J. & Pillai, R.S.
Science. 2012 Aug 3;337(6094):529-30. PubMed
piRNAs and their involvement in male germline development in mice.
Pillai, R.S. & Chuma, S.
Dev Growth Differ. 2012 Jan 6. doi: 10.1111/j.1440-169X.2011.01320.x. PubMed
Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing.
Reuter, M., Berninger, P., Chuma, S., Shah, H., Hosokawa, M., Funaya, C., Antony, C., Sachidanandam, R. & Pillai, R.S.
Nature. 2011 Nov 27;480(7376):264-7. doi: 10.1038/nature10672. PubMed
Tudor domain containing 7 (Tdrd7) is essential for dynamic ribonucleoprotein (RNP) remodeling of chromatoid bodies during spermatogenesis.
Tanaka, T., Hosokawa, M., Vagin, V.V., Reuter, M., Hayashi, E., Mochizuki, A.L., Kitamura, K., Yamanaka, H., Kondoh, G., Okawa, K., Kuramochi-Miyagawa, S., Nakano, T., Sachidanandam, R., Hannon, G.J., Pillai, R.S., Nakatsuji, N. & Chuma, S.
Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10579-84. Epub 2011 Jun 13. PubMed
Recognition of 2'-O-methylated 3'-end of piRNA by the PAZ domain of a Piwi protein.
Simon, B., Kirkpatrick, J.P., Eckhardt, S., Reuter, M., Rocha, E.A., Andrade-Navarro, M.A., Sehr, P., Pillai, R.S. & Carlomagno, T.
Structure. 2011 Feb 9;19(2):172-80. Epub 2011 Jan 20. PubMed
Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway.
Zheng, K., Xiol, J., Reuter, M., Eckardt, S., Leu, N.A., McLaughlin, K.J., Stark, A., Sachidanandam, R., Pillai, R.S. & Wang, P.J.
Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11841-6. Epub 2010 Jun 1. PubMed
The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline.
Shoji, M., Tanaka, T., Hosokawa, M., Reuter, M., Stark, A., Kato, Y., Kondoh, G., Okawa, K., Chujo, T., Suzuki, T., Hata, K., Martin, S.L., Noce, T., Kuramochi-Miyagawa, S., Nakano, T., Sasaki, H., Pillai, R.S., Nakatsuji, N. & Chuma, S.
Dev Cell. 2009 Dec;17(6):775-87. PubMed
Retrotransposon silencing by piRNAs: ping-pong players mark their sub-cellular boundaries.
Chuma, S. & Pillai, R.S.
PLoS Genet. 2009 Dec;5(12):e1000770. Epub . PubMed
Loss of the Mili-interacting Tudor domain-containing protein-1 activates transposons and alters the Mili-associated small RNA profile.
Reuter, M., Chuma, S., Tanaka, T., Franz, T., Stark, A. & Pillai, R.S.
Nat Struct Mol Biol. 2009 Jun;16(6):639-46. Epub 2009 May 24. PubMed
MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F.
Mathonnet, G., Fabian, M.R., Svitkin, Y.V., Parsyan, A., Huck, L., Murata, T., Biffo, S., Merrick, W.C., Darzynkiewicz, E., Pillai, R.S., Filipowicz, W., Duchaine, T.F. & Sonenberg, N.
Science. 2007 Sep 21;317(5845):1764-7. Epub 2007 Jul 26. PubMed
Repression of protein synthesis by miRNAs: how many mechanisms?
Pillai, R.S., Bhattacharyya, S.N. & Filipowicz, W.
Trends Cell Biol. 2007 Mar;17(3):118-26. Epub 2007 Jan 2. PubMed
Effects of Dicer and Argonaute down-regulation on mRNA levels in human HEK293 cells.
Schmitter, D., Filkowski, J., Sewer, A., Pillai, R.S., Oakeley, E.J., Zavolan, M., Svoboda, P. & Filipowicz, W.
Nucleic Acids Res. 2006;34(17):4801-15. Epub 2006 Sep 13. PubMed
MicroRNA function: multiple mechanisms for a tiny RNA?
Pillai, R.S.
RNA. 2005 Dec;11(12):1753-61. PubMed
Inhibition of translational initiation by Let-7 MicroRNA in human cells.
Pillai, R.S., Bhattacharyya, S.N., Artus, C.G., Zoller, T., Cougot, N., Basyuk, E., Bertrand, E. & Filipowicz, W.
Science. 2005 Sep 2;309(5740):1573-6. Epub 2005 Aug 4. PubMed
Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis.
Pillai, R.S., Artus, C.G. & Filipowicz, W.
RNA. 2004 Oct;10(10):1518-25. Epub 2004 Aug 30. PubMed
