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Staff at EMBL

Aurelien Deniaud

Postdoctoral Fellow (EIPOD)
Schaffitzel Team

EMBL Grenoble, 71 avenue des Martyrs, CS 90181, 38042 Grenoble Cedex 9, France

E-mail: send a mail


Structural and functional analysis of the three MIF4G domains of nonsense-mediated decay factor UPF2. Clerici, M., Deniaud, A., Boehm, V., Gehring, N.H., Schaffitzel, C. & Cusack, S. Nucleic Acids Res. 2014 Feb;42(4):2673-86. doi: 10.1093/nar/gkt1197. Epub 2013Nov 23. Europe PMC

Directly from the source: endogenous preparations of molecular machines. Mesa, P., Deniaud, A., Montoya, G. & Schaffitzel, C. Curr Opin Struct Biol. 2013 Jun;23(3):319-25. doi: 10.1016/ 2013 Feb 8. Europe PMC

The respiratory-dependent assembly of ANT1 differentially regulates Bax and Ca2+ mediated cytochrome c release. Benjamin, F., Rodrigue, R., Aurelien, D., Christophe, R., Stephane, C., Monique, M., Catherine, B. & Thierry, L. Front Biosci (Elite Ed). 2011 Jan 1;3:395-409. Europe PMC

Lactococcus lactis, an alternative system for functional expression of peripheral and intrinsic Arabidopsis membrane proteins. Frelet-Barrand, A., Boutigny, S., Moyet, L., Deniaud, A., Seigneurin-Berny, D., Salvi, D., Bernaudat, F., Richaud, P., Pebay-Peyroula, E., Joyard, J. & Rolland, N. PLoS One. 2010 Jan 20;5(1):e8746. Europe PMC

Crystallography of membrane proteins: from crystallization to structure. Deniaud, A., Moiseeva, E., Gordeliy, V. & Pebay-Peyroula, E. Methods Mol Biol. 2010;654:79-103. doi: 10.1007/978-1-60761-762-4_5. Europe PMC

Role of the permeability transition pore complex in lethal inter-organelle crosstalk. Sharaf El Dein, O., Gallerne, C., Deniaud, A., Brenner, C. & Lemaire, C. Front Biosci. 2009 Jan 1;14:3465-82. Europe PMC

Differences between CusA and AcrB crystallisation highlighted by protein flexibility. Deniaud, A., Goulielmakis, A., Coves, J. & Pebay-Peyroula, E. PLoS One. 2009 Jul 10;4(7):e6214. Europe PMC

Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis. Deniaud, A., Sharaf el dein, O., Maillier, E., Poncet, D., Kroemer, G., Lemaire, C. & Brenner, C. Oncogene. 2008 Jan 10;27(3):285-99. Epub 2007 Aug 13. Europe PMC

GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization. Tarze, A., Deniaud, A., Le Bras, M., Maillier, E., Molle, D., Larochette, N., Zamzami, N., Jan, G., Kroemer, G. & Brenner, C. Oncogene. 2007 Apr 19;26(18):2606-20. Epub 2006 Oct 30. Europe PMC

Voltage-dependent anion channel transports calcium ions through biomimetic membranes. Deniaud, A., Rossi, C., Berquand, A., Homand, J., Campagna, S., Knoll, W., Brenner, C. & Chopineau, J. Langmuir. 2007 Mar 27;23(7):3898-905. Epub 2007 Feb 22. Europe PMC

Targeted Vpr-derived peptides reach mitochondria to induce apoptosis of alphaVbeta3-expressing endothelial cells. Borgne-Sanchez, A., Dupont, S., Langonne, A., Baux, L., Lecoeur, H., Chauvier, D., Lassalle, M., Deas, O., Briere, J.J., Brabant, M., Roux, P., Pechoux, C., Briand, J.P., Hoebeke, J., Deniaud, A., Brenner, C., Rustin, P., Edelman, L., Rebouillat, D. & Jacotot, E. Cell Death Differ. 2007 Mar;14(3):422-35. Epub 2006 Aug 4. Europe PMC

Chemosensitization by knockdown of adenine nucleotide translocase-2. Le Bras, M., Borgne-Sanchez, A., Touat, Z., El Dein, O.S., Deniaud, A., Maillier, E., Lecellier, G., Rebouillat, D., Lemaire, C., Kroemer, G., Jacotot, E. & Brenner, C. Cancer Res. 2006 Sep 15;66(18):9143-52. Europe PMC

Inhibition of caspase-dependent mitochondrial permeability transition protects airway epithelial cells against mustard-induced apoptosis. Sourdeval, M., Lemaire, C., Deniaud, A., Taysse, L., Daulon, S., Breton, P., Brenner, C., Boisvieux-Ulrich, E. & Marano, F. Apoptosis. 2006 Sep;11(9):1545-59. Europe PMC

Therapeutic peptides: Targeting the mitochondrion to modulate apoptosis. Jacotot, E., Deniaud, A., Borgne-Sanchez, A., Touat, Z., Briand, J.P., Le Bras, M. & Brenner, C. Biochim Biophys Acta. 2006 Sep-Oct;1757(9-10):1312-23. Epub 2006 Jul 14. Europe PMC

Peptido-targeting of the mitochondrial transition pore complex for therapeutic apoptosis induction. Deniaud, A., Hoebeke, J., Briand, J.P., Muller, S., Jacotot, E. & Brenner, C. Curr Pharm Des. 2006;12(34):4501-11. Europe PMC

Inhibition of adenine nucleotide translocator pore function and protection against apoptosis in vivo by an HIV protease inhibitor. Weaver, J.G., Tarze, A., Moffat, T.C., Lebras, M., Deniaud, A., Brenner, C., Bren, G.D., Morin, M.Y., Phenix, B.N., Dong, L., Jiang, S.X., Sim, V.L., Zurakowski, B., Lallier, J., Hardin, H., Wettstein, P., van Heeswijk, R.P., Douen, A., Kroemer, R.T., Hou, S.T., Bennett, S.A., Lynch, D.H., Kroemer, G. & Badley, A.D. J Clin Invest. 2005 Jul;115(7):1828-38. Europe PMC

Toxic epidermal necrolysis: effector cells are drug-specific cytotoxic T cells. Nassif, A., Bensussan, A., Boumsell, L., Deniaud, A., Moslehi, H., Wolkenstein, P., Bagot, M. & Roujeau, J.C. J Allergy Clin Immunol. 2004 Nov;114(5):1209-15. Europe PMC

Dynamic evolution of the adenine nucleotide translocase interactome during chemotherapy-induced apoptosis. Verrier, F., Deniaud, A., Lebras, M., Metivier, D., Kroemer, G., Mignotte, B., Jan, G. & Brenner, C. Oncogene. 2004 Oct 21;23(49):8049-64. Europe PMC

Mitochondrial membrane permeabilization by HIV-1 Vpr. Deniaud, A., Brenner, C. & Kroemer, G. Mitochondrion. 2004 Jul;4(2-3):223-33. Europe PMC

The chemopreventive agent N-(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family. Boya, P., Morales, M.C., Gonzalez-Polo, R.A., Andreau, K., Gourdier, I., Perfettini, J.L., Larochette, N., Deniaud, A., Baran-Marszak, F., Fagard, R., Feuillard, J., Asumendi, A., Raphael, M., Pau, B., Brenner, C. & Kroemer, G. Oncogene. 2003 Sep 18;22(40):6220-30. Europe PMC