EMBL Grenoble, 71 avenue des Martyrs, CS 90181, 38042 Grenoble Cedex 9, France

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  • PhD in Physics, 1994, University Grants Commission Doctoral Fellow, University of Mysore, India.
    Lecturer, Govt. Science College, Bangalore / Visiting Researcher, IISc, Bangalore, India:1994-1998.
    Alexander von Humboldt Research Fellow, Berlin, Germany: 1998-2000.
    Postdoctoral work at University of California at Santa Cruz, USA; Biotechnology Research Institute, Montreal, Canada; Max Delbruck Center for Molecular Medicine, Berlin, Germany: 2000-2004.
    Scientist at Brookhaven National Laboratory, New York / Case Western Reserve University, USA : 2004-2009.
    Staff Scientist at EMBL Grenoble, France since 2010.


Total: 31 publication(s)


Manjasetty BA, Halavaty AS, Luan CH, Osipiuk J, Mulligan R, Kwon K, Anderson WF, Joachimiak A. (2016)

Fluorescence-based thermal shift data on multidrug regulator AcrR from Salmonella enterica subsp. entrica serovar Typhimurium str. LT2.

Data Brief 7:537-539. doi: 10.1016/j.dib.2016.03.003
Europe PMC | doi

Manjasetty BA, Halavaty AS, Luan CH, Osipiuk J, Mulligan R, Kwon K, Anderson WF, Joachimiak A. (2016)

Loop-to-helix transition in the structure of multidrug regulator AcrR at the entrance of the drug-binding cavity.

J Struct Biol doi: 10.1016/j.jsb.2016.01.008
Europe PMC | doi


Singh AK, Manjasetty B, Balasubramani GL, Koul S, Kaushik A, Ekka MK, Singh V, Kumaran S. (2015)

Crystal Structure of Fad35R from Mycobacterium tuberculosis H37Rv in the Apo-State.

PLoS ONE 10(5):e0124333. doi: 10.1371/journal.pone.0124333
Europe PMC | doi


Kumar S, Aslam S, Mazumder M, Dahiya P, Murmu A, Manjasetty BA, Zaidi R, Bhattacharya A, Gourinath S. (2014)

Crystal Structure of Calcium Binding Protein-5 from Entamoeba histolytica and Its Involvement in Initiation of Phagocytosis of Human Erythrocytes.

PLoS Pathog. 10(12) doi: 10.1371/journal.ppat.1004532
Europe PMC | doi

Dann R, Lansky S, Lavid N, Zehavi A, Belakhov V, Baasov T, Dvir H, Manjasetty B, Belrhali H, Shoham Y, Shoham G. (2014)

Preliminary crystallographic analysis of Xyn52B2, a GH52 β-D-xylosidase from Geobacillus stearothermophilus T6.

Acta Crystallogr F Struct Biol Commun 70(Pt 12):1675-1682. doi: 10.1107/s2053230x14023887
Europe PMC | doi

Manjasetty BA, Chance MR, Burley SK, Panjikar S, Almo SC. (2014)

Crystal structure of Clostridium acetobutylicum Aspartate kinase (CaAK): An important allosteric enzyme for amino acids production

Biotechnol Rep (Amst) 3:73-85. doi: 10.1016/j.btre.2014.06.009
Europe PMC | doi

Lansky S, Salama R, Dann R, Shner I, Manjasetty BA, Belrhali H, Shoham Y, Shoham G. (2014)

Cloning, purification and preliminary crystallographic analysis of Ara127N, a GH127 β-L-arabinofuranosidase from Geobacillus stearothermophilus T6

Acta Crystallogr F Struct Biol Commun 70(Pt 8):1038-1045. doi: 10.1107/s2053230x14012680
Europe PMC | doi

Srivastav R, Kumar D, Grover A, Singh A, Manjasetty BA, Sharma R, Taneja B. (2014)

Unique subunit packing in mycobacterial nanoRNase leads to alternate substrate recognitions in DHH phosphodiesterases.

Nucleic Acids Res. 42(12):7894-7910. doi: 10.1093/nar/gku425
Europe PMC | doi

Lassaux P, Conchillo-Solé O, Manjasetty BA, Yero D, Perletti L, Belrhali H, Daura X, Gourlay LJ, Bolognesi M. (2014)

Redefining the PF06864 Pfam family based on Burkholderia pseudomallei PilO2(Bp) S-SAD crystal structure.

PLoS ONE 9(4):e94981. doi: 10.1371/journal.pone.0094981
Europe PMC | doi


Kumar S, Farmer R, Turnbull AP, Tripathy NK, Manjasetty BA. (2013)

Structural and functional conservation profiles of novel cathepsin L-like proteins identified in the Drosophila melanogaster genome

J. Biomol. Struct. Dyn. 31(12):1481-1489. doi: 10.1080/07391102.2012.745379
Europe PMC | doi

Paradzik T, Ivic N, Filic Z, Manjasetty BA, Herron P, Luic M, Vujaklija D. (2013)

Structure-function relationships of two paralogous single-stranded DNA-binding proteins from Streptomyces coelicolor: implication of SsbB in chromosome segregation during sporulation

Nucleic Acids Res. 41(6):3659-3672. doi: 10.1093/nar/gkt050
Europe PMC | doi


Manjasetty BA, Yu XH, Panjikar S, Taguchi G, Chance MR, Liu CJ. (2012)

Structural basis for modification of flavonol and naphthol glucoconjugates by Nicotiana tabacum malonyltransferase (NtMaT1)

Planta 236(3):781-793. doi: 10.1007/s00425-012-1660-8
Europe PMC | doi

Manjasetty BA, Büssow K, Panjikar S, Turnbull AP. (2012)

Current methods in structural proteomics and its applications in biological sciences

3 Biotech 2(2):89-113. doi: 10.1007/s13205-011-0037-1
Europe PMC | doi

Srivastava SK, Gayathri S, Manjasetty BA, Gopal B. (2012)

Analysis of conformational variation in macromolecular structural models

PLoS ONE 7(7):e39993. doi: 10.1371/journal.pone.0039993
Europe PMC | doi


Cafasso J, Manjasetty BA, Karr EA, Sandman K, Chance MR, Reeve JN. (2010)

Preliminary crystallography confirms that the archaeal DNA-binding and tryptophan-sensing regulator TrpY is a dimer

Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66(Pt 11):1493-1495. doi: 10.1107/s1744309110036031
Europe PMC | doi

Manjasetty B, Turnbull A, Panjikar S. (2010)

The impact of structural proteomics on biotechnology

Biotechnol. Genet. Eng. Rev. 26:353-370.
Europe PMC


Manjasetty BA, Turnbull AP, Panjikar S, Büssow K, Chance MR. (2008)

Automated technologies and novel techniques to accelerate protein crystallography for structural genomics

Proteomics 8(4):612-625. doi: 10.1002/pmic.200700687
Europe PMC | doi


Manjasetty BA, Shi W, Zhan C, Fiser A, Chance MR. (2007)

A high-throughput approach to protein structure analysis

Genet. Eng. (N.Y.) 28:105-128.
Europe PMC


Manjasetty BA, Chance MR. (2006)

Crystal structure of Escherichia coli L-arabinose isomerase (ECAI), the putative target of biological tagatose production

J. Mol. Biol. 360(2):297-309. doi: 10.1016/j.jmb.2006.04.040
Europe PMC | doi

Manjasetty BA, Büssow K, Fieber-Erdmann M, Roske Y, Gobom J, Scheich C, Götz F, Niesen FH, Heinemann U. (2006)

Crystal structure of Homo sapiens PTD012 reveals a zinc-containing hydrolase fold

Protein Sci. 15(4):914-920. doi: 10.1110/ps.052037006
Europe PMC | doi


Zhan C, Fedorov EV, Shi W, Ramagopal UA, Thirumuruhan R, Manjasetty BA, Almo SC, Fiser A, Chance MR, Fedorov AA. (2005)

The ybeY protein from Escherichia coli is a metalloprotein

Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 61(Pt 11):959-963. doi: 10.1107/s1744309105031131
Europe PMC | doi

Shi W, Zhan C, Ignatov A, Manjasetty BA, Marinkovic N, Sullivan M, Huang R, Chance MR. (2005)

Metalloproteomics: high-throughput structural and functional annotation of proteins in structural genomics

Structure 13(10):1473-1486. doi: 10.1016/j.str.2005.07.014
Europe PMC | doi

Manjasetty BA, Niesen FH, Scheich C, Roske Y, Goetz F, Behlke J, Sievert V, Heinemann U, Büssow K. (2005)

X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1)

BMC Struct. Biol. 5:21. doi: 10.1186/1472-6807-5-21
Europe PMC | doi


Manjasetty BA, Niesen FH, Delbrück H, Götz F, Sievert V, Büssow K, Behlke J, Heinemann U. (2004)

X-ray structure of fumarylacetoacetate hydrolase family member Homo sapiens FLJ36880

Biol. Chem. 385(10):935-942. doi: 10.1515/bc.2004.122
Europe PMC | doi

Manjasetty BA, Quedenau C, Sievert V, Büssow K, Niesen F, Delbrück H, Heinemann U. (2004)

X-ray structure of human gankyrin, the product of a gene linked to hepatocellular carcinoma

Proteins 55(1):214-217. doi: 10.1002/prot.20028
Europe PMC | doi

Manjasetty BA, Delbrück H, Pham DT, Mueller U, Fieber-Erdmann M, Scheich C, Sievert V, Büssow K, Niesen FH, Weihofen W, Loll B, Saenger W, Heinemann U. (2004)

Crystal structure of Homo sapiens protein hp14.5

Proteins 54(4):797-800. doi: 10.1002/prot.10619
Europe PMC | doi

Manjasetty BA, Hennecke J, Glockshuber R, Heinemann U. (2004)

Structure of circularly permuted DsbA(Q100T99): preserved global fold and local structural adjustments

Acta Crystallogr. D Biol. Crystallogr. 60(Pt 2):304-309. doi: 10.1107/s0907444903028695
Europe PMC | doi


Manjasetty BA, Powlowski J, Vrielink A. (2003)

Crystal structure of a bifunctional aldolase-dehydrogenase: sequestering a reactive and volatile intermediate

Proc. Natl. Acad. Sci. U.S.A. 100(12):6992-6997. doi: 10.1073/pnas.1236794100
Europe PMC | doi

Manjasetty BA, Höppner K, Mueller U, Heinemann U. (2003)

Secure web book to store structural genomics research data

J. Struct. Funct. Genomics 4(2-3):121-127. doi: 10.1023/a:1026169519592
Europe PMC | doi


Manjasetty BA, Croteau N, Powlowski J, Vrielink A. (2001)

Crystallization and preliminary X-ray analysis of dmpFG-encoded 4-hydroxy-2-ketovalerate aldolase--aldehyde dehydrogenase (acylating) from Pseudomonas sp. strain CF600

Acta Crystallogr. D Biol. Crystallogr. 57(Pt 4):582-585. doi: 10.1107/s0907444901000439
Europe PMC | doi


Decanniere K, Babu AM, Sandman K, Reeve JN, Heinemann U. (2000)

Crystal structures of recombinant histones HMfA and HMfB from the hyperthermophilic archaeon Methanothermus fervidus

J. Mol. Biol. 303(1):35-47. doi: 10.1006/jmbi.2000.4104
Europe PMC | doi