EMBL Grenoble, 71 avenue des Martyrs, CS 90181, 38042 Grenoble Cedex 9, France


  • PhD 1999, University of Basel.
    Postdoctoral research at Harvard University, Boston.
    Group leader at EMBL Grenoble since 2007.


Total: 21 publication(s)


Rengachari S, Groiss S, Devos JM, Caron E, Grandvaux N, Panne D. (2018)

Structural basis of STAT2 recognition by IRF9 reveals molecular insights into ISGF3 function.

Proc. Natl. Acad. Sci. U.S.A. doi: 10.1073/pnas.1718426115
Europe PMC | doi


Sauer PV, Timm J, Liu D, Sitbon D, Boeri-Erba E, Velours C, Mücke N, Langowski J, Ochsenbein F, Almouzni G, Panne D. (2017)

Insights into the molecular architecture and histone H3-H4 deposition mechanism of yeast Chromatin assembly factor 1.

Elife 6 doi: 10.7554/elife.23474
Europe PMC | doi

Kaczmarska Z, Ortega E, Goudarzi A, Huang H, Kim S, Márquez JA, Zhao Y, Khochbin S, Panne D. (2017)

Structure of p300 in complex with acyl-CoA variants

Nat. Chem. Biol. 13(1):21-29. doi: 10.1038/nchembio.2217
Europe PMC | doi


Aguilar-Gurrieri C, Larabi A, Vinayachandran V, Patel NA, Yen K, Reja R, Ebong IO, Schoehn G, Robinson CV, Pugh BF, Panne D. (2016)

Structural evidence for Nap1-dependent H2A-H2B deposition and nucleosome assembly.

EMBO J. 35(13):1465-1482. doi: 10.15252/embj.201694105
Europe PMC | doi

Goudarzi A, Zhang D, Huang H, Barral S, Kwon OK, Qi S, Tang Z, Buchou T, Vitte AL, He T, Cheng Z, Montellier E, Gaucher J, Curtet S, Debernardi A, Charbonnier G, Puthier D, Petosa C, Panne D, Rousseaux S, Roeder RG, Zhao Y, Khochbin S. (2016)

Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters.

Mol. Cell 62(2):169-180. doi: 10.1016/j.molcel.2016.03.014
Europe PMC | doi

Muir KW, Kschonsak M, Li Y, Metz J, Haering CH, Panne D. (2016)

Structure of the Pds5-Scc1 Complex and Implications for Cohesin Function.

Cell Rep 14(9):2116-2126. doi: 10.1016/j.celrep.2016.01.078
Europe PMC | doi


Delvecchio M, Gaucher J, Aguilar-Gurrieri C, Ortega E, Panne D. (2013)

Structure of the p300 catalytic core and implications for chromatin targeting and HAT regulation

Nat. Struct. Mol. Biol. 20(9):1040-1046. doi: 10.1038/nsmb.2642
Europe PMC | doi

Panne D. (2013)

Immunology: Cytosolic DNA sensing unraveled

Nat. Chem. Biol. 9(9):533-534. doi: 10.1038/nchembio.1318
Europe PMC | doi

Larabi A, Devos JM, Ng SL, Nanao MH, Round A, Maniatis T, Panne D. (2013)

Crystal structure and mechanism of activation of TANK-binding kinase 1

Cell Rep 3(3):734-746. doi: 10.1016/j.celrep.2013.01.034
Europe PMC | doi


Reynoird N, Schwartz BE, Delvecchio M, Sadoul K, Meyers D, Mukherjee C, Caron C, Kimura H, Rousseaux S, Cole PA, Panne D, French CA, Khochbin S. (2010)

Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains

EMBO J. 29(17):2943-2952. doi: 10.1038/emboj.2010.176
Europe PMC | doi


Shen A, Higgins DE, Panne D. (2009)

Recognition of AT-rich DNA binding sites by the MogR repressor

Structure 17(5):769-777. doi: 10.1016/j.str.2009.02.018
Europe PMC | doi


Panne D. (2008)

The enhanceosome

Curr. Opin. Struct. Biol. 18(2):236-242. doi: 10.1016/j.sbi.2007.12.002
Europe PMC | doi


Panne D, McWhirter SM, Maniatis T, Harrison SC. (2007)

Interferon regulatory factor 3 is regulated by a dual phosphorylation-dependent switch

J. Biol. Chem. 282(31):22816-22822. doi: 10.1074/jbc.m703019200
Europe PMC | doi

Panne D, Maniatis T, Harrison SC. (2007)

An atomic model of the interferon-beta enhanceosome

Cell 129(6):1111-1123. doi: 10.1016/j.cell.2007.05.019
Europe PMC | doi


Panne D, Maniatis T, Harrison SC. (2004)

Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-beta enhancer

EMBO J. 23(22):4384-4393. doi: 10.1038/sj.emboj.7600453
Europe PMC | doi


Panne D, Müller SA, Wirtz S, Engel A, Bickle TA. (2001)

The McrBC restriction endonuclease assembles into a ring structure in the presence of G nucleotides

EMBO J. 20(12):3210-3217. doi: 10.1093/emboj/20.12.3210
Europe PMC | doi


Stewart FJ, Panne D, Bickle TA, Raleigh EA. (2000)

Methyl-specific DNA binding by McrBC, a modification-dependent restriction enzyme

J. Mol. Biol. 298(4):611-622. doi: 10.1006/jmbi.2000.3697
Europe PMC | doi

Evans TC Jr, Martin D, Kolly R, Panne D, Sun L, Ghosh I, Chen L, Benner J, Liu XQ, Xu MQ. (2000)

Protein trans-splicing and cyclization by a naturally split intein from the dnaE gene of Synechocystis species PCC6803

J. Biol. Chem. 275(13):9091-9094. doi: 10.1074/jbc.275.13.9091
Europe PMC | doi


Panne D, Raleigh EA, Bickle TA. (1999)

The McrBC endonuclease translocates DNA in a reaction dependent on GTP hydrolysis

J. Mol. Biol. 290(1):49-60. doi: 10.1006/jmbi.1999.2894
Europe PMC | doi


Panne D, Raleigh EA, Bickle TA. (1998)

McrBs, a modulator peptide for McrBC activity

EMBO J. 17(18):5477-5483. doi: 10.1093/emboj/17.18.5477
Europe PMC | doi

Southworth MW, Adam E, Panne D, Byer R, Kautz R, Perler FB. (1998)

Control of protein splicing by intein fragment reassembly

EMBO J. 17(4):918-926. doi: 10.1093/emboj/17.4.918
Europe PMC | doi