EMBL Grenoble, 71 avenue des Martyrs, CS 90181, 38042 Grenoble Cedex 9, France


  • PhD 2002, University of Bern.
    Postdoctoral research at the Friedrich Miescher Institute, Basel.
    Group Leader at EMBL Grenoble since 2006-16. Visiting Group Leader since 2016.
    ERC Investigator.


Total: 12 publication(s)


Mathonnet G, Fabian MR, Svitkin YV, Parsyan A, Huck L, Murata T, Biffo S, Merrick WC, Darzynkiewicz E, Pillai RS, Filipowicz W, Duchaine TF, Sonenberg N. (2007)

MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F

Science 317(5845):1764-1767. doi: 10.1126/science.1146067
Europe PMC | doi


Schmitter D, Filkowski J, Sewer A, Pillai RS, Oakeley EJ, Zavolan M, Svoboda P, Filipowicz W. (2006)

Effects of Dicer and Argonaute down-regulation on mRNA levels in human HEK293 cells

Nucleic Acids Res. 34(17):4801-4815. doi: 10.1093/nar/gkl646
Europe PMC | doi


Pillai RS. (2005)

MicroRNA function: multiple mechanisms for a tiny RNA?

RNA 11(12):1753-1761. doi: 10.1261/rna.2248605
Europe PMC | doi

Azzouz TN, Pillai RS, Däpp C, Chari A, Meister G, Kambach C, Fischer U, Schümperli D. (2005)

Toward an assembly line for U7 snRNPs - Interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes.

J Biol Chem 280(41):34435-34440. doi: 10.1074/jbc.M505077200
Europe PMC | doi

Pillai RS, Bhattacharyya SN, Artus CG, Zoller T, Cougot N, Basyuk E, Bertrand E, Filipowicz W. (2005)

Inhibition of translational initiation by Let-7 MicroRNA in human cells

Science 309(5740):1573-1576. doi: 10.1126/science.1115079
Europe PMC | doi

Xu HZ, Pillai RS, Azzouz TN, Shpargel KB, Kambach C, Hebert MD, Schümperli D, Matera AG. (2005)

The C-terminal domain of coilin interacts with Sm proteins and U snRNPs.

Chromosoma 114(3):155-166. doi: 10.1007/s00412-005-0003-y
Europe PMC | doi

Filipowicz W, Jaskiewicz L, Kolb FA, Pillai RS. (2005)

Post-transcriptional gene silencing by siRNAs and miRNAs.

Curr Opin Struct Biol 15(3):331-341. doi: 10.1016/j.sbi.2005.05.006
Europe PMC | doi


Pillai RS, Artus CG, Filipowicz W. (2004)

Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis

RNA 10(10):1518-1525. doi: 10.1261/rna.7131604
Europe PMC | doi

Schümperli D, Pillai R. (2004)

The special Sm core structure of the U7 snRNP: far-reaching significance of a small nuclear ribonucleoprotein.

Cell Mol Life Sci 61(19-20):2560-2570. doi: 10.1007/s00018-004-4190-0
Europe PMC | doi


Pillai RS, Grimmler M, Meister G, Will CL, Lührmann R, Fischer U, Schümperli D. (2003)

Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing.

Genes Dev 17(18):2321-2333. doi: 10.1101/gad.274403
Europe PMC | doi


Pillai RS, Will CL, Lührmann R, Schümperli D, Müller B. (2001)

Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein.

EMBO J 20(19):5470-5479. doi: 10.1093/emboj/20.19.5470
Europe PMC | doi

Meister G, Bühler D, Pillai R, Lottspeich F, Fischer U. (2001)

A multiprotein complex mediates the ATP-dependent assembly of spliceosomal U snRNPs.

Nat Cell Biol 3(11):945-949. doi: 10.1038/ncb1101-945
Europe PMC | doi