BM14 was bending magnet 14 beamline at the ESRF, optimised for exploiting anomalous scattering methods MAD/SAD in macromolecular structure determination. BM14 had an optical design suited to the rapid and accurate energy change between 7 and 17 kev, which covers most of the commonly used absorption edges of heavy atoms. Between 2010 and 2016, BM14 provided beamtime and support to scientists from India (via Department of Biotechnology (DBT) funding) and Europe (via European Synchrotron Radiation Facility (ESRF) funding and the BioStruct-X European Commission Programme) on the basis of peer-reviewed beamtime proposals.
Research focus and operation
Research at BM14 has centred on the elucidation of protein structures by X-ray crystallography. The beamline has been a partner in a number of collaborative research projects with INDIA, UK and European funded initiatives focused on structural biology, namely: SPINE, eHTPX, INSTRUCT and BioStruct-X.
Until 2001, BM14 was operated by the ESRF, starting from its inception in 1995. From 2001, the beamline was run as a Collaborative Research Group Beamline (CRG) shared between UK and Spanish funding agencies. During 2003-2009, BM14 provided beamtime for UK and EMBL macromolecular crystallography (MX) community as UK CRG. Between 2010 and 2016, the beamline was operated as part of the EMBL-ESRF project with India, which joined ESRF as a member state in 2017.
Beamline 14’s legacy (16 February 2017)
Looking back at beamline 14's achievements with EMBL Grenoble staff scientist Hassan Belrhali
NOTE: For all users publishing data collected on BM14 please do add the following sentence in the acknowledgments: